Methylcrotonyl-CoA carboxylase 2 supports leucine catabolism to promote mitochondrial biogenesis and alleviate cisplatin-induced acute kidney injury
MCCC2 supported leucine catabolism and promoted mitochondrial biogenesis, providing a new therapeutic strategy for cisplatin-induced AKI.
Authors
- Li Hu (ORCID: https://orcid.org/0009-0009-3554-807X)
- Kangqiang Weng
- Hao Qi (ORCID: https://orcid.org/0000-0001-8922-4593)
- Huiyue Qi (ORCID: https://orcid.org/0000-0002-8263-4589)
- Yingbo Dai (ORCID: https://orcid.org/0000-0003-1089-416X)
- Luyao She (ORCID: https://orcid.org/0009-0009-0276-151X)
- Junliang Qiu
Institutions
- Sun Yat-sen University (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Kidney Research and Clinical Practice
- Published
- 2025-01-09
- DOI
- https://doi.org/10.23876/j.krcp.24.169
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00