Efficacy of tranilast in preventing exacerbating cardiac function and death from heart failure in muscular dystrophy patients with advanced-stage heart failure: a single-arm, open-label, multicenter study
The study was registered in the UMIN Clinical Trials Registry (UMIN-CTR: UMIN000031965, URL: http://www.umin.ac.jp/ctr/ ) [March 30, 2018] and the Japan Registry of Clinical Trials (jRCT, registration number: jRCTs031180038, URL: https://jrct.niph.go.jp/ ) [November 12, 2021]. Patient registration was initiated on December 19, 2018.
Authors
- Akinori Nakamura (ORCID: https://orcid.org/0000-0002-4259-1297)
- Toshiaki Takahashi (ORCID: https://orcid.org/0000-0002-8188-2505)
- Yuko Iwata (ORCID: https://orcid.org/0000-0003-2432-5179)
- Tsuyoshi Matsumura (ORCID: https://orcid.org/0000-0001-6241-3626)
- Ruriko Kitao
- Hiroya Hashimoto (ORCID: https://orcid.org/0000-0003-1865-4953)
- Masanori Asakura (ORCID: https://orcid.org/0000-0002-9872-671X)
- Kazuhiko Segawa (ORCID: https://orcid.org/0000-0001-9641-3181)
- Masahiro Sekimizu (ORCID: https://orcid.org/0000-0002-9438-2673)
- Akiko Saito (ORCID: https://orcid.org/0000-0003-3723-8445)
- Koichi Kimura (ORCID: https://orcid.org/0000-0003-1020-3904)
- Takuhisa Tamura
- Takayasu Fukudome
- Satoshi Kuru
- Yasufumi Motoyoshi
- Chigusa Watanabe
Institutions
- Hyogo Medical University (JP)
- Sendai Nishitaga National Hospital (JP)
- Nagasaki Kawatana Medical Center (JP)
- National Center of Neurology and Psychiatry (JP)
- Toneyama National Hospital (JP)
- National Cerebral and Cardiovascular Center (JP)
- National Hospital Organization (JP)
- Nagoya Medical Center (JP)
- Matsumoto University (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1186/s13023-025-03538-1
- Citations
- 4
- Primary Topic
- Ion Channels and Receptors
- Type
- article
- Field-Weighted Citation Impact
- 5.86