Indirect determination of hemoglobin A2 reference intervals in Pakistani infants using data mining
This study supports data mining as an alternative method for establishing HbA2 RIs, especially in resource-limited settings. The results are specific to the studied population, instrument, and reagent, and they elucidate the fluctuations in HbA2 synthesis with age. These intervals will enhance clinical decision-making based on HbA2 results.
Authors
- Sibtain Ahmed (ORCID: https://orcid.org/0000-0003-0316-2622)
- Muhammad Shariq Shaikh (ORCID: https://orcid.org/0000-0003-2938-7416)
- Saba Farrukh
- Shahnawaz Bayunus
Institutions
- Leeds Teaching Hospitals NHS Trust (GB)
- Aga Khan University Hospital (PK)
Publication Details
- Journal
- BMC Medical Informatics and Decision Making
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1186/s12911-025-02857-4
- Citations
- 1
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.63