Activation of the WNT4/ β-catenin/FOXO1 pathway by PDK1 promotes cervical cancer metastasis and EMT process
Targeting PDK1 may provide novel therapeutic strategies specifically for CC by modulating the WNT4/β-catenin/FOXO1 pathway and associated EMT and apoptotic processes.
Authors
- Honglang Huang (ORCID: https://orcid.org/0000-0003-4060-0599)
- Shi-Dong Chen (ORCID: https://orcid.org/0000-0002-1114-622X)
- Cuixia Zhang (ORCID: https://orcid.org/0000-0002-1674-0535)
- Yuhuan Wang (ORCID: https://orcid.org/0000-0002-7487-1402)
- Guolin Hong (ORCID: https://orcid.org/0000-0003-0641-9438)
- Mingjian Lian
Institutions
- First Affiliated Hospital of Xiamen University (CN)
Publication Details
- Journal
- Journal of Molecular Histology
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1007/s10735-024-10342-x
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81