Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

We identified several crucial genes and pathways linked to the onset and development of PCOS. Our findings offer a clear connection between PCOS and GCERS, clarify the molecular mechanisms driving PCOS progression, and offer new perspectives for discovering valuable therapeutic targets and potential biomarkers for the condition.

Authors

Xiaoqing Liu (ORCID: https://orcid.org/0000-0002-1309-5454)
Yan Zhang (ORCID: https://orcid.org/0000-0001-9794-8014)
Xiujuan Chen (ORCID: https://orcid.org/0000-0003-1409-4741)
Lin Yuan (ORCID: https://orcid.org/0000-0002-9694-8191)
Xiumei Xiong (ORCID: https://orcid.org/0009-0006-9220-516X)

Institutions

Fujian Medical University (CN)
Fuzhou Maternity and Child Health Care Hospital (CN)

Publication Details

Journal: Frontiers in Molecular Biosciences
Published: 2025-01-09
DOI: https://doi.org/10.3389/fmolb.2024.1504015
Citations: 1
Primary Topic: Endoplasmic Reticulum Stress and Disease
Type: article
Field-Weighted Citation Impact: 1.15

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article

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

Xiaoqing Liu, Yan Zhang, Xiujuan Chen, Lin Yuan et al.

Jan 9, 2025

1 citations

Frontiers in Molecular Biosciences

Endoplasmic Reticulum Stress and Disease

1.15

article

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

Xiaoqing Liu, Yan Zhang, Xiujuan Chen, Lin Yuan, Xiumei Xiong

January 9, 2025article en

1 citations

Abstract

We identified several crucial genes and pathways linked to the onset and development of PCOS. Our findings offer a clear connection between PCOS and GCERS, clarify the molecular mechanisms driving PCOS progression, and offer new perspectives for discovering valuable therapeutic targets and potential biomarkers for the condition.

Frontiers in Molecular BiosciencesVol. 11

Fujian Medical University (CN), Fuzhou Maternity and Child Health Care Hospital (CN)

Good health and well-being

Openalex Percentile: Top 29%

Endoplasmic Reticulum Stress and Disease

1.15

DOI Open Access PDF OpenAlex

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Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis — Xiaoqing Liu, Yan Zhang, et al. · Frontiers in Molecular Biosciences (2025) | TGRS Research Map | TGRS