Identification of Lauric Acid as a Potent Sodium Channel NaV1.5 Blocker from Compound Chinese Medicine Wenxin Keli
Lauric acid is a potent blocker for sodium channel Na<sub>V</sub>1.5 and alleviates arrhythmia via inhibiting I<sub>Na</sub>.
Authors
- Hong‐Hua Wu (ORCID: https://orcid.org/0000-0002-3089-4282)
- Boyong Zhang
- Nan Guo (ORCID: https://orcid.org/0000-0002-6946-0107)
- Yan Zhu (ORCID: https://orcid.org/0000-0002-3197-7936)
- Chenxing Huang
- Taiyi A. Wang (ORCID: https://orcid.org/0000-0002-5933-6866)
- Weiwei Xie (ORCID: https://orcid.org/0000-0001-8611-4858)
- Yingran Liang
- Xiaonan Chen
- Lin Wu (ORCID: https://orcid.org/0000-0003-1041-1500)
- Xi Yao (ORCID: https://orcid.org/0000-0002-5341-6443)
- Yuefei Wang (ORCID: https://orcid.org/0000-0002-0278-4625)
- Jiaming Gao (ORCID: https://orcid.org/0000-0003-2821-2921)
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Shandong University of Traditional Chinese Medicine (CN)
- Peking University (CN)
- Xiyuan Hospital (CN)
- Peking University First Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2147/dddt.s485723
- Citations
- 2
- Primary Topic
- Cardiac electrophysiology and arrhythmias
- Type
- article
- Field-Weighted Citation Impact
- 2.78