Combining single-cell analysis and molecular docking techniques to construct a prognostic model for colon adenocarcinoma and uncovering inhibin subunit βb as a novel therapeutic target
In summary, our research, based on the expression characteristics of ARGs, provides new insights into the precise classification, prognosis assessment, and identification of potential therapeutic targets in COAD. It also validates the key role of INHBB in the progression of COAD, establishing the foundation for future personalized treatment strategies.
Authors
- Yongdong Niu (ORCID: https://orcid.org/0000-0002-5392-3736)
- Peijun Zuo
- Luxiao Zhang (ORCID: https://orcid.org/0009-0006-4164-3442)
- Jiaxin Lu (ORCID: https://orcid.org/0000-0001-6356-3220)
- Mengyu Zhao
- Ye Lu
- Yanping Yu (ORCID: https://orcid.org/0000-0003-4091-1610)
- Qinqing Wu
- Yuwei Wu
Institutions
- Fujian Medical University (CN)
- Anhui Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shantou University (CN)
- Shantou University Medical College (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3389/fimmu.2024.1524560
- Citations
- 2
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.04