Balancing act: optimizing blue light for melanogenesis while minimizing cellular damage in primary human skin cells
Moderate-intensity blue light at 10 mW/cm<sup>2</sup>, 15 J/cm<sup>2</sup> effectively stimulates melanogenesis while maintaining cellular metabolic activity in both keratinocytes and melanocytes, offering a promising, safe approach for blue light therapies targeting pigmentation disorders.
Authors
- Brice Magne (ORCID: https://orcid.org/0000-0001-5052-1144)
- Lucie Germain (ORCID: https://orcid.org/0000-0001-8883-6491)
- Natallia E. Uzunbajakava (ORCID: https://orcid.org/0000-0003-4524-7528)
- Augustin C. Barolet (ORCID: https://orcid.org/0000-0003-3919-2890)
- Karel Ferland (ORCID: https://orcid.org/0000-0003-0715-3854)
- Daniel Barolet
Institutions
- McGill University Health Centre (CA)
- Centre hospitalier de l'Université Laval (CA)
- Holst Centre (Netherlands) (NL)
- Université Laval (CA)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3389/fphys.2024.1513054
- Citations
- 1
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- Fondation des pompiers du Québec pour les grands brûlés
- Canadian Institutes of Health Research
- Fonds de Recherche du Québec - Santé