A family with normal sperm motility carrying a sY86 deletion in AZFa region and partial deletion in AZFc region
Given the complexities of the reproductive phenotype following AZF region deletions, additional extended genetic testing is necessary when partial deletions in the AZF region are detected, thus providing more accurate predictions of the spermatogenesis in patient. This study provides valuable insights and guidance for clinical decision-making and the implementation of assisted reproductive technologies in such cases.
Authors
- Weiwei Zhi
- Jiuzhi Zeng
- Dongsheng Xiong (ORCID: https://orcid.org/0000-0003-4829-7520)
- Xingrong Du (ORCID: https://orcid.org/0000-0001-6427-9600)
- Guohui Zhang (ORCID: https://orcid.org/0000-0001-6905-0637)
- Weixin Liu (ORCID: https://orcid.org/0000-0002-1650-0371)
- Yuhong Zhao (ORCID: https://orcid.org/0000-0002-6806-521X)
- Ningjing Li (ORCID: https://orcid.org/0000-0002-9157-4899)
Institutions
- Chengdu Medical College (CN)
- Chengdu Women's and Children's Central Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3389/fgene.2024.1519774
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chengdu Medical College