Clinical characteristics and immunotherapy response in paraneoplastic neurologic syndrome patients with increased number of high-risk antibodies
Psychobehavioral abnormality, bowel and bladder dysfunction, and total protein of CSF were three variables associated with increased number of high-risk antibodies in PNS patients, while increased number of high-risk antibodies might indicate a poor immunotherapy response. Our findings might help to understand the association of PNS patients' clinical features and high-risk antibodies, as well as to guide clinical practice.
Authors
- Jiaojin Jiang
- Fei Gao (ORCID: https://orcid.org/0000-0003-4856-0261)
- Cheng Huang (ORCID: https://orcid.org/0000-0003-3427-5937)
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Guo Meng (ORCID: https://orcid.org/0000-0003-2076-0982)
- Gong Wang (ORCID: https://orcid.org/0000-0003-1670-9084)
- Chen Mao (ORCID: https://orcid.org/0000-0002-6537-6215)
- Qian He
- Rui‐Hua Xu (ORCID: https://orcid.org/0000-0001-9771-8534)
- Maohua Li (ORCID: https://orcid.org/0009-0003-4570-2591)
Institutions
- Army Medical University (CN)
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3389/fimmu.2024.1520493
- Citations
- 2
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Army Medical University