Long term outcomes associated with the use of perioperative systemic chemotherapy on low grade appendiceal mucinous neoplasms with pseudomyxoma peritonei treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
In this multicenter retrospective study, the receipt of perioperative chemotherapy was associated with worse long-term outcomes among patients with LAMN undergoing CRS-HIPEC. Systemic chemotherapy may lead to patient deconditioning and contribute to worse long-term outcomes. It should not be recommended outside of a clinical trial.
Authors
- Charles A. Staley
- Keith F. Fournier (ORCID: https://orcid.org/0000-0002-7882-9826)
- Gyulnara G. Kasumova
- Travis E. Grotz (ORCID: https://orcid.org/0000-0002-7753-097X)
- Jula Veerapong (ORCID: https://orcid.org/0000-0002-6124-2586)
- Seán Dineen (ORCID: https://orcid.org/0000-0002-2012-2238)
- Alex C. Kim
- Callisia N. Clarke (ORCID: https://orcid.org/0000-0002-5229-961X)
- Samantha M. Ruff (ORCID: https://orcid.org/0000-0001-5275-6705)
- Jordan M. Cloyd (ORCID: https://orcid.org/0000-0002-2373-8433)
- Oliver S. Eng (ORCID: https://orcid.org/0000-0003-0226-5005)
- Laura Lambert (ORCID: https://orcid.org/0000-0001-8494-0590)
- Sameer H. Patel (ORCID: https://orcid.org/0000-0001-6442-1857)
- Daniel E. Abbott (ORCID: https://orcid.org/0000-0002-5539-0734)
- Mustafa Raoof (ORCID: https://orcid.org/0000-0003-4710-2226)
- Manoj Palavalli
- Fabian M. Johnston
Institutions
- The University of Texas MD Anderson Cancer Center (US)
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3389/fonc.2024.1456920
- Citations
- 3
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 6.02