Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1

The transcriptome changes in tumor cells infected by oHSV-1 may be utilized to predict oncolytic efficacy and provide rational strategies for designing next-generation oncolytic viruses.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-01-09
DOI
https://doi.org/10.3389/fonc.2024.1469511
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1

Majid Shahbazi, Naeme Javid, Shahriyar Abdoli
Frontiers in Oncology
Virus-based gene therapy research
article

Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1

Majid Shahbazi, Naeme Javid, Shahriyar Abdoli
article en

Abstract

The transcriptome changes in tumor cells infected by oHSV-1 may be utilized to predict oncolytic efficacy and provide rational strategies for designing next-generation oncolytic viruses.

Frontiers in OncologyVol. 14
Golestan University (IR), Golestan University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 100%
Virus-based gene therapy research
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