Berberrubine protects against cisplatin-induced ototoxicity by promoting folate biosynthesis
Our findings suggest that BB protects against cisplatin-induced hearing damage by enhancing folate biosynthesis, decreasing intracellular ROS levels, and inhibiting apoptosis.
Authors
- Changling Sun (ORCID: https://orcid.org/0000-0002-0462-3163)
- Zhuang Miao (ORCID: https://orcid.org/0000-0002-6200-2306)
- Xiaodong Du (ORCID: https://orcid.org/0000-0003-4381-2802)
- Danyang Chang
Institutions
- Jiangnan University (CN)
- Wuxi Fourth People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3389/fphar.2024.1496917
- Citations
- 3
- Primary Topic
- Synthesis of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Southeast University