Structural analysis, <i>in vitro</i> anti-tubercular activities, and <i>in silico</i> ADMET evaluation of ethyl 7-methoxy-3-(4-substituted benzoyl)indolizine-1-carboxylates

A series of indolizine derivatives were synthesized and characterized by SC-XRD and computational analysis to investigate their structural aspects, as well as their anti-tubercular activity, with varying substituents.

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Publication Details

Journal
CrystEngComm
Published
2025-01-01
DOI
https://doi.org/10.1039/d4ce01018c
Citations
5
Primary Topic
Synthesis and Reactivity of Heterocycles
Type
article
Field-Weighted Citation Impact
4.68
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article

Structural analysis, in vitro anti-tubercular activities, and in silico ADMET evaluation of ethyl 7-methoxy-3-(4-substituted benzoyl)indolizine-1-carboxylates

Katharigatta Narayanaswamy Venugopala, Rahul D. Nagdeve, Melendhran Pillay, Gourav Rakshit et al.
5 citations
CrystEngComm
Synthesis and Reactivity of Heterocycles
4.68
article

Structural analysis, in vitro anti-tubercular activities, and in silico ADMET evaluation of ethyl 7-methoxy-3-(4-substituted benzoyl)indolizine-1-carboxylates

Katharigatta Narayanaswamy Venugopala, Rahul D. Nagdeve, Melendhran Pillay, Gourav Rakshit, Pradip Kumar Mondal, Pran Kishore Deb, Sandeep Chandrashekharappa, Jyoti Swarup Thakur, Susanta K. Nayak, Osama I. Alwassil, Keshab M. Bairagi, Maurizio Polentarutti
article en
5 citations

Abstract

A series of indolizine derivatives were synthesized and characterized by SC-XRD and computational analysis to investigate their structural aspects, as well as their anti-tubercular activity, with varying substituents.

CrystEngCommVol. 27(12)
National Health Laboratory Service (ZA), Birla Institute of Technology, Mesra (IN), Visvesvaraya National Institute of Technology (IN), Durban University of Technology (ZA), King Saud bin Abdulaziz University for Health Sciences (SA), Elettra-Sincrotrone Trieste S.C.p.A. (IT), Gondwana University (IN), National Institute of Pharmaceutical Education and Research (IN), King Faisal University (SA)
Good health and well-being
Openalex Percentile: Top 6%
Synthesis and Reactivity of Heterocycles
4.68
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