Prevention and Control of Cervical Cancer by WHO-Endorsed Guidelines for Visual Inspection with Acetic Acid (Via) as a Simple Screening Method

Despite the availability of primary prevention through Human Papillomavirus (HPV) vaccination, cervical cancer remains one of the leading causes of cancer-related deaths among women worldwide. And imposes an enormous global public health burden most notably for those living in low- or middle-income countries. Objective: To determine the diagnostic accuracy of VIA in diagnosing cervical cancer as compared to conventional methods. Methods: This retrospective study analyzed a cohort of women who underwent VIA screening for cervical cancer at Divisional Headquarters Teaching Hospital. The sample included 1,200 women aged 25-65 who had not been screened for cervical cancer in the previous three years. VIA screening followed WHO-recommended procedures, with presumptive diagnoses made through naked eye examination based on WHO guidelines for low-resource settings. Data was entered and analyzed by SPSS 25.0. Results: Among 1,200 women screened for cervical abnormalities using VIA, 280 tested positive (23.3%). The highest VIA-positive rates were in the 45-54 age group (112 positives), followed by the 35-44 group (70 positives). The diagnostic accuracy of VIA for cervical abnormalities shows high sensitivity (89.34%) and specificity (96.23%). VIA's positive predictive value was 85.83%, while the negative predictive value was 97.25%, indicating reliable detection of true positives and negatives. Conclusions: VIA was an accurate, affordable screening tool with a high level of sensitivity and specificity in detecting cervical precancerous lesions, particularly for low-resource settings. These results highlight the effectiveness of VIA screening across age groups, with higher detection rates in women over 35.

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Publication Details

Journal
Pakistan Journal of Health Sciences
Published
2024-12-31
DOI
https://doi.org/10.54393/pjhs.v5i12.2494
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
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article

Prevention and Control of Cervical Cancer by WHO-Endorsed Guidelines for Visual Inspection with Acetic Acid (Via) as a Simple Screening Method

Sania Ratyal, Nazia Hameed, Ayesha Fatima, MA Khan et al.
Pakistan Journal of Health Sciences
Cervical Cancer and HPV Research
article

Prevention and Control of Cervical Cancer by WHO-Endorsed Guidelines for Visual Inspection with Acetic Acid (Via) as a Simple Screening Method

Sania Ratyal, Nazia Hameed, Ayesha Fatima, MA Khan, Shazia Saeed, Sara Akram
article en

Abstract

Despite the availability of primary prevention through Human Papillomavirus (HPV) vaccination, cervical cancer remains one of the leading causes of cancer-related deaths among women worldwide. And imposes an enormous global public health burden most notably for those living in low- or middle-income countries. Objective: To determine the diagnostic accuracy of VIA in diagnosing cervical cancer as compared to conventional methods. Methods: This retrospective study analyzed a cohort of women who underwent VIA screening for cervical cancer at Divisional Headquarters Teaching Hospital. The sample included 1,200 women aged 25-65 who had not been screened for cervical cancer in the previous three years. VIA screening followed WHO-recommended procedures, with presumptive diagnoses made through naked eye examination based on WHO guidelines for low-resource settings. Data was entered and analyzed by SPSS 25.0. Results: Among 1,200 women screened for cervical abnormalities using VIA, 280 tested positive (23.3%). The highest VIA-positive rates were in the 45-54 age group (112 positives), followed by the 35-44 group (70 positives). The diagnostic accuracy of VIA for cervical abnormalities shows high sensitivity (89.34%) and specificity (96.23%). VIA's positive predictive value was 85.83%, while the negative predictive value was 97.25%, indicating reliable detection of true positives and negatives. Conclusions: VIA was an accurate, affordable screening tool with a high level of sensitivity and specificity in detecting cervical precancerous lesions, particularly for low-resource settings. These results highlight the effectiveness of VIA screening across age groups, with higher detection rates in women over 35.

Pakistan Journal of Health Sciences
Divisional Headquarters Teaching Hospital Mirpur (PK)
No poverty
Openalex Percentile: Top 63%
Cervical Cancer and HPV Research
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