The combination of fatigue with the serum GCSF improves the performance of serological screening for frailty
Frailty is a critical cause leading to elderly death. No drug is available to treat it, while prevention works. However, reliable blood screening and diagnostic methods for frailty are still lacking. Here, we show that the serum GCSF, in combination with the fatigue factor of the frailty scale, can improve the performance of serological screening for frailty.
Authors
- Zhijun Bao (ORCID: https://orcid.org/0000-0002-0900-7204)
- Yixuan Qiu (ORCID: https://orcid.org/0000-0003-0481-6923)
- Chaobao Zhang (ORCID: https://orcid.org/0000-0002-4413-3193)
- Jiaofeng Wang
- Jie Chen (ORCID: https://orcid.org/0000-0003-3435-0351)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-6314-4146)
- Xiangqi Li (ORCID: https://orcid.org/0000-0003-2675-0574)
- Xueying Ji
- Jiaming Yu (ORCID: https://orcid.org/0009-0002-0746-0563)
Institutions
- Second Military Medical University (CN)
- Fudan University (CN)
- Huadong Hospital (CN)
- Shanghai Institutes for Biological Sciences (CN)
- Center for Excellence in Molecular Cell Science (CN)
- Shanghai Pudong New Area Gongli Hospital (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Acta Biochimica et Biophysica Sinica
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3724/abbs.2025007
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China