Research on the Effects of High Fructose Corn Syrup on the Fatty Liver Disease and Cardiovascular Disease

Excessive intake of added sugars and fructose has been associated with leading to adverse health outcomes. This article reviews the effects of sugar intake in a variety of ways, categorized as increased body weight fat, fatty liver (NAFLD), and cardiovascular-related diseases in humans. The analysis showed that decreasing consumption of sugar and sugar products significantly reduced weight, whereas increasing consumption of sugar and sugar products, especially from sugary beverages, led to weight gain. In addition, excessive intake of high sugar is associated with the accumulation of liver fat, a key factor contributing to the increased incidence of fatty liver. The findings highlight the key role of fructose, especially from high fructose corn syrup, in promoting metabolic dysfunction. In conclusion, reducing intake of added sugars is critical to preventing chronic disease and improving public health. Subsequent studies should explore individual differences in response to sugar metabolism and the long-term effects of interventions for small intakes of sugar.