Identification of crucial extracellular genes as potential biomarkers in newly diagnosed Type 1 diabetes <i>via</i> integrated bioinformatics analysis
The nine identified key extracellular genes, particularly <i>LCN2, IFNG, TNF</i>, and <i>MMP9</i>, may be potential diagnostic biomarkers for NT1D. Our findings provide new insights into the molecular mechanisms and novel therapeutic targets of NT1D.
Authors
- Yuchen Hua (ORCID: https://orcid.org/0009-0007-4141-4559)
- Wei Shao (ORCID: https://orcid.org/0000-0003-1763-9911)
- Lingyu Zhang
- Ming Gao (ORCID: https://orcid.org/0000-0002-2743-2247)
- Fatema Tabak (ORCID: https://orcid.org/0000-0002-1240-3451)
- Qian Li
- Qing Liu (ORCID: https://orcid.org/0000-0001-9021-7665)
- Yang Liu (ORCID: https://orcid.org/0000-0002-9442-700X)
- Yangyang Li (ORCID: https://orcid.org/0009-0003-2578-856X)
Institutions
- Nanjing Medical University (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-01-09
- DOI
- https://doi.org/10.7717/peerj.18660
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China