Exploring the association between familial hemiplegic migraine genes (<i>CACNA1A</i>, <i>ATP1A2</i> and <i>SCN1A</i>) with migraine and epilepsy: A UK Biobank exome-wide association study
Heterozygous genotypes in all three FHM genes were associated with migraine but not epilepsy in this genotype-focused study. Homozygous <i>SCN1A</i> genotypes also showed increased disease risk of migraine, yet these carriers were protected against epilepsy.
Authors
- Christian Staehr (ORCID: https://orcid.org/0000-0001-5431-4409)
- Flemming W. Bach (ORCID: https://orcid.org/0000-0002-2518-9335)
- Mette Nyegaard (ORCID: https://orcid.org/0000-0003-4973-8543)
- Vladimir V. Matchkov (ORCID: https://orcid.org/0000-0002-3303-1095)
- Palle Duun Rohde (ORCID: https://orcid.org/0000-0003-4347-8656)
Institutions
- Statens Serum Institut (DK)
- Aarhus University (DK)
- Aalborg University Hospital (DK)
- Aarhus University Hospital (DK)
- Aalborg University (DK)
Publication Details
- Journal
- Cephalalgia
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1177/03331024241306103
- Citations
- 3
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Riisfort Fonden