Metal-directed hierarchical superhelices from hybrid peptide foldamers
A superhelix is a three-dimensional arrangement of a helix in which the helix is coiled around a common axis. Here, we are reporting a short 12-helix of α,γ-hybrid peptides terminated by metal binding ligands, self-assembled into a right-handed superhelix around a common axis in the presence of Cd(II) ions. Furthermore, these superhelices are assembled into hierarchical superhelical β-sheet-type structural motifs in single crystals. The results reported here may give new insights to construct advanced self-assembled architectures from peptide foldamers.
Authors
- Souvik Roy (ORCID: https://orcid.org/0000-0003-0146-5283)
- Sachin A. Nalawade (ORCID: https://orcid.org/0000-0002-6987-561X)
- Hosahudya N. Gopi (ORCID: https://orcid.org/0000-0001-8156-9271)
- Sanjit Dey (ORCID: https://orcid.org/0000-0001-6534-0522)
- Manjeet Singh (ORCID: https://orcid.org/0000-0001-6820-9992)
- Souvik Panda Mahapatra (ORCID: https://orcid.org/0009-0007-7151-8818)
- DRGKoppalu R. Puneeth Kumar (ORCID: https://orcid.org/0000-0002-3501-4440)
- Sandip U. Toraskar
Institutions
- Indian Institute of Science Education and Research Pune (IN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d4cc05770h
- Citations
- 1
- Primary Topic
- Chemical Synthesis and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.81