The expression of exosomal and cellular miRNAs in predicting oxaliplatin resistance in colorectal cancer cells: an in silico and in vitro study
The low expression of miR-454-3p, miR-7974, and miR-3615 in CRC cells or high expression of miR-130b-3p and miR-4326 in isolated exosomes could predict the response to oxaliplatin therapy. This indicates the potential of these specific miRNAs to serve as predictive markers for the response to oxaliplatin therapy.
Authors
- Mohammad Hossein Ghahremani (ORCID: https://orcid.org/0000-0001-5051-6214)
- Gholamreza Tavoosidana (ORCID: https://orcid.org/0000-0002-1079-7434)
- Ebrahim Eftekhar (ORCID: https://orcid.org/0000-0002-4519-0595)
- Yazdan Asgari (ORCID: https://orcid.org/0000-0001-6993-6956)
- Hoda Deli
- Zeynab Vakili-Ghartavol
Institutions
- Hormozgan University of Medical Sciences (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1186/s12885-024-13392-2
- Citations
- 6
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 5.62
Funders
- Tehran University of Medical Sciences and Health Services
- Hormozgan University of Medical Sciences