Neuroprotective potential of isofraxidin: Alleviating parkinsonian symptoms, inflammation and microglial activation
Isofraxidin exhibits notable neuroprotective properties by mitigating LPS-induced parkinsonian behaviors, microglial activation, inflammation, and dopaminergic neuron damage. These results highlight isofraxidin's potential as a therapeutic intervention for PD.
Authors
- Jui‐Hu Shih (ORCID: https://orcid.org/0000-0001-7884-1246)
- I‐Hsun Li (ORCID: https://orcid.org/0000-0002-2824-4774)
- Chieh-Wen Chang
- Chih‐Chien Cheng (ORCID: https://orcid.org/0000-0003-1645-8457)
- Tsung–Ta Liu (ORCID: https://orcid.org/0000-0002-8865-0272)
- Hao-Yuan Hung (ORCID: https://orcid.org/0000-0001-6455-3032)
- Li-Yun Fann (ORCID: https://orcid.org/0000-0001-9800-3987)
- T.C. Wang (ORCID: https://orcid.org/0009-0003-7701-1234)
- Sheng‐Shian Li (ORCID: https://orcid.org/0000-0003-4727-8870)
- Pei-Yeh Yu
- Ying-Che Huang
Institutions
- Fu Jen Catholic University (TW)
- Tri-Service General Hospital (TW)
- National Taipei University of Nursing and Health Science (TW)
- Taipei City Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Journal of Central Nervous System Disease
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1177/11795735241312661
- Citations
- 3
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.17
Funders
- Tri-Service General Hospital
- National Science and Technology Council