Impact of Heart Transplant Allocation Changes on Waitlist Mortality and Clinical Practice in Pediatric and Adult Patients With Congenital Heart Disease and Cardiomyopathy
The recent allocation changes of the Organ Procurement and Transplantation Network associations with waitlist duration and outcome were not uniform across pediatric and adult cohorts with CHD or those with cardiomyopathy. Children with cardiomyopathy and adults with CHD did not experience the mortality benefits experienced by adults with cardiomyopathy and children with CHD. Future iterations of the allocation systems should consider differential access to mechanical circulatory support options for children and adults, patient sensitization status, and whether having separate systems for adults and children is the most appropriate method to allocate organs.
Authors
- Luke Wooster (ORCID: https://orcid.org/0000-0001-6179-9766)
- Carol Wittlieb‐Weber (ORCID: https://orcid.org/0000-0002-1299-3201)
- Joseph William Rossano (ORCID: https://orcid.org/0000-0002-8284-0673)
- Matthew J. O’Connor (ORCID: https://orcid.org/0000-0003-3012-5464)
- Jonathan B. Edelson (ORCID: https://orcid.org/0000-0003-3220-7922)
- Humera Ahmed (ORCID: https://orcid.org/0000-0002-1572-4840)
- Kimberly Y. Lin (ORCID: https://orcid.org/0000-0003-1582-9797)
- Jonathan J. Edwards (ORCID: https://orcid.org/0000-0002-8153-7066)
- Constantine Mavroudis (ORCID: https://orcid.org/0009-0003-6773-7939)
- Xuemei Zhang (ORCID: https://orcid.org/0000-0003-0705-4231)
- Katsuhide Maeda
Institutions
- Children's Hospital of Philadelphia (US)
- Health Outcomes Solutions (United States) (US)
- J.P. Morgan (GB)
- University of Pennsylvania (US)
Publication Details
- Journal
- Circulation
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1161/circulationaha.124.072335
- Citations
- 9
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 18.06