Antimicrobial activity of Scutellaria L. plant extracts

The work deals with the evaluating the antimicrobial activity of ethanolic extracts of different plant organs (roots, leaves, buds) of three species of Scutellaria genus: S. albida L., S. altissima L., S. baicalensis L., grown in M.M. Gryshko National Botanical Garden of the National Academy of Sciences of Ukraine, against gram-negative (Pseudomonas aeruginosa, Escherichia coli and Serratia marcescens) and gram-positive (Staphylococcus aureus) microorganisms. Analysis of the effect of ethanolic extracts of juvenile Scutellaria plants on bacterial cultures showed that S. albida had the highest inhibitory potential, as it inhibited the growth of all bacterial test objects. S. creticola extracts effected both gram-positive bacteria and gram-negative Staphylococcus aureus. The extracts of S. altissima and S. baicalensis juvenile plants were characterized by their activity against two gram-positive test objects – Escherichia coli and Pseudomonas aeruginosa. The analysis of the antibacterial activity of ethanolic fractions of the extracts of Scutellaria individual organs showed that the highest inhibitory effect was demonstrated by the extracts of leaves and roots of S. baicalensis against Escherichia coli, the leaves and roots of S. albida against Staphylococcus aureus, and S. albida of against Pseudomonas aeruginosa. The results confirmed the antimicrobial effect of different Scutellaria species, so that these plants could be used for the treatment of bacterial infections.