Efficacy of Emerging Digital Screening Tools in Detecting Cognitive Impairment Among Low Educational Elderly in Western China: A Community‐Based Study

Abstract Background This study investigated the efficacy of emerging digital screening tools for detecting cognitive impairment (CI) in a large community of elderly individuals with lower educational backgrounds. Method This community‐based cohort study included 1083 participants (age≥65 years), 337 of whom were diagnosed with CI (64.1%≤6 years). We utilized three types of tools: traditional tests (AD8 and MMSE), a digitally improved Mini‐Cog scale, and digital behavioral tools (gait and eye movement tests). We construct LightGBM machine learning models of different digital screening tools and their combinations and evaluate their performance. The correlation between each model’s top 10 key features and cognitive domain scores was analyzed. Result Emerging digital screening tools [AUC: eye movement (0.89)> digital Mini‐Cog (0.86)> gait (0.83)] showed promising efficacy in distinguishing CI from NC. The AUC of combination 1(digital Mini‐Cog & gait) was 0.89, and that of combination 2(eye movement & gait) was improved to 0.93. Combination 3 (eye movement & digital Mini‐Cog) achieved the highest classification efficacy (AUC = 0.96), with accuracy, sensitivity, and specificity all above 83%. In the subgroup analysis (≤6 years), the AUC for eye movement in identifying CI decreased to 0.74. Different behavioral features reflected varying impairments across cognitive domains. Conclusion Emerging digital technologies offer objective, accurate, and efficient alternatives for CI detection, and are anticipated to replace traditional tests in community screenings. But the applicability of these tools in lower educational groups (≤6 years) should be cautious.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.095764
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy of Emerging Digital Screening Tools in Detecting Cognitive Impairment Among Low Educational Elderly in Western China: A Community‐Based Study

Xiaonan Zhang, Yang Li
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

Efficacy of Emerging Digital Screening Tools in Detecting Cognitive Impairment Among Low Educational Elderly in Western China: A Community‐Based Study

Xiaonan Zhang, Yang Li
article en

Abstract

Abstract Background This study investigated the efficacy of emerging digital screening tools for detecting cognitive impairment (CI) in a large community of elderly individuals with lower educational backgrounds. Method This community‐based cohort study included 1083 participants (age≥65 years), 337 of whom were diagnosed with CI (64.1%≤6 years). We utilized three types of tools: traditional tests (AD8 and MMSE), a digitally improved Mini‐Cog scale, and digital behavioral tools (gait and eye movement tests). We construct LightGBM machine learning models of different digital screening tools and their combinations and evaluate their performance. The correlation between each model’s top 10 key features and cognitive domain scores was analyzed. Result Emerging digital screening tools [AUC: eye movement (0.89)> digital Mini‐Cog (0.86)> gait (0.83)] showed promising efficacy in distinguishing CI from NC. The AUC of combination 1(digital Mini‐Cog & gait) was 0.89, and that of combination 2(eye movement & gait) was improved to 0.93. Combination 3 (eye movement & digital Mini‐Cog) achieved the highest classification efficacy (AUC = 0.96), with accuracy, sensitivity, and specificity all above 83%. In the subgroup analysis (≤6 years), the AUC for eye movement in identifying CI decreased to 0.74. Different behavioral features reflected varying impairments across cognitive domains. Conclusion Emerging digital technologies offer objective, accurate, and efficient alternatives for CI detection, and are anticipated to replace traditional tests in community screenings. But the applicability of these tools in lower educational groups (≤6 years) should be cautious.

Alzheimer s & DementiaVol. 20(S8)
Shanxi Medical University (CN), First Hospital of Shanxi Medical University (CN)
Quality Education
Openalex Percentile: Top 65%
Dementia and Cognitive Impairment Research
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Efficacy of Emerging Digital Screening Tools in Detecting Cognitive Impairment Among Low Educational Elderly in Western China: A Community‐Based Study — Xiaonan Zhang, Yang Li · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS