Comprehensive Exploration of Unexplained Dyspnoea in Subjects with Normal Ejection Fraction and Low Natriuretic Peptides

The most common causes of unexplained exertional dyspnoea in patients without significant elevation of natriuretic peptides are peripheral deconditioning, HFpEF and hyperventilation. Studying patients during exercise allows for getting more data about pathophysiology and improving patient phenotyping and management. Early unmasking of HFpEF using exercise echocardiography and/or CPX and initiation of treatment could prevent hospitalizations for acute heart failure. Although using exercise testing, many patients could not be classified according to their diagnosis, and this reinforces the need to better define exercise diagnostic criteria.

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Publication Details

Journal
ESC Heart Failure
Published
2025-01-09
DOI
https://doi.org/10.1002/ehf2.15059
Citations
1
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
1.39

Funders

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article

Comprehensive Exploration of Unexplained Dyspnoea in Subjects with Normal Ejection Fraction and Low Natriuretic Peptides

Patrick Jourdain, Jean‐Michel Tartière, Barnabas Gellen, Antoine Beurnier et al.
1 citations
ESC Heart Failure
Heart Failure Treatment and Management
1.39
article

Comprehensive Exploration of Unexplained Dyspnoea in Subjects with Normal Ejection Fraction and Low Natriuretic Peptides

Patrick Jourdain, Jean‐Michel Tartière, Barnabas Gellen, Antoine Beurnier, Emmanuelle Berthelot, Olivier Lairez, Tarek Laouar, J.C. Eicher, Nataliya Hrynchynshyn
article en
1 citations

Abstract

The most common causes of unexplained exertional dyspnoea in patients without significant elevation of natriuretic peptides are peripheral deconditioning, HFpEF and hyperventilation. Studying patients during exercise allows for getting more data about pathophysiology and improving patient phenotyping and management. Early unmasking of HFpEF using exercise echocardiography and/or CPX and initiation of treatment could prevent hospitalizations for acute heart failure. Although using exercise testing, many patients could not be classified according to their diagnosis, and this reinforces the need to better define exercise diagnostic criteria.

ESC Heart FailureVol. 12(2)
Université Toulouse III - Paul Sabatier (FR), Université de Toulon (FR), Inserm (FR), Université Paris-Saclay (FR), Université de Poitiers (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre Hospitalier Universitaire de Poitiers (FR), CHU Dijon Bourgogne (FR), Hôpital Marie Lannelongue (FR), Hôpital Paris Saint-Joseph (FR), Bicêtre Hospital (FR)
Société Française de Cardiologie
Good health and well-being
Openalex Percentile: Top 24%
Heart Failure Treatment and Management
1.39
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Comprehensive Exploration of Unexplained Dyspnoea in Subjects with Normal Ejection Fraction and Low Natriuretic Peptides — Patrick Jourdain, Jean‐Michel Tartière, et al. · ESC Heart Failure (2025) | TGRS Research Map | TGRS