Innovative Applications of Rotary Evaporators in Vacuum-assisted Synthesis for Sustainable Chemistry

In recent years, the pursuit of sustainable and efficient methods for organic synthesis has gained significant momentum. Among the emerging strategies, vacuum-assisted organic synthesis is a promising approach, offering the potential to expedite reactions, boost yields, and minimize waste generation. This review delves into the innovative utilization of rotary evaporators as a reactor for vacuum-assisted organic synthesis, showcasing their unique advantages and potential. The advantages of this approach and the recent examples of vacuum-accelerated reactions carried out in rotary evaporators are discussed, demonstrating their versatility and potential for green catalysis. By exploring the untapped potential of rotary evaporators as reactors, we aim to stimulate further research in this burgeoning field and contribute to the ongoing endeavour to transform organic synthesis into a more sustainable and efficient practice.