Ossifying Lipoma: A Rare And Intriguing Case Report

Ossifying lipoma is a rare benign tumour composed of mature adipocytes and bony tissue. It can occur in various locations, but it is extremely uncommon in the oral cavity. The clinical presentation is usually asymptomatic or with mild pain. The radiological features vary depending on the degree of ossification and necrosis within the lesion. Histological examination is essential for the definitive diagnosis, as ossifying lipoma can mimic other benign or malignant bone tumours. Surgical excision is the most preferred treatment option, and it offers excellent prognosis. The etiology and pathogenesis are unknown, but two main theories have been proposed: multidirectional differentiation of mesenchymal cells or metaplastic transformation of adipocytes. Here, we illustrate a rare case of ossifying lipoma of a 52-year-old male patient, who presented with a soft tissue growth. This case showcases the importance of considering ossifying lipoma in the differential diagnosis of oral soft tissue lesions, especially in unusual locations.