Melt Electrowriting for Biomimetic Tissue Engineering: Advances in Scaffold Design, Materials, and Multifunctional Applications
ABSTRACT Melt electrowriting (MEW) is an emerging 3D printing technology that can precisely fabricate micro‐nano fibrous scaffolds and has significant application prospects in tissue engineering. This paper reviews the latest progress of MEW in tissue engineering scaffold fabrication, including its working principle, key design factors, and various processable biomaterials. The enhancement of scaffold function through filler addition, post‐treatment modification, and combining MEW with other manufacturing technologies are discussed. The application of MEW in bone, cartilage, blood vessel, nerve, and periodontal tissue engineering is analyzed. Finally, the challenges MEW technology faces, such as material limitations, equipment reliability, and process complexity, are highlighted, and future development directions to promote the wide application of MEW in biomedical and other fields are proposed.
Authors
- Yunlei Yin (ORCID: https://orcid.org/0000-0003-4313-1169)
- Cheng Guo (ORCID: https://orcid.org/0000-0001-6882-2949)
- Wenyuan Han (ORCID: https://orcid.org/0000-0002-9636-6415)
- Qianqian Mu
- Dongyi Chen (ORCID: https://orcid.org/0000-0001-8112-183X)
- Hao Yang (ORCID: https://orcid.org/0000-0003-1348-2005)
- Hongying Yang (ORCID: https://orcid.org/0000-0003-2524-053X)
Institutions
- Zhongyuan University of Technology (CN)
- University of Electronic Science and Technology of China (CN)
- Tiangong University (CN)
Publication Details
- Journal
- Polymers for Advanced Technologies
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/pat.70067
- Citations
- 13
- Primary Topic
- Electrospun Nanofibers in Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 7.76
Funders
- National Natural Science Foundation of China