Maxillary sinus augmentation utilizing Xenograft, Bichat`s fat pad tissue and low-level light therapy – cone beam computed tomography and resonance frequency analysis results of a prospective randomized clinical study

Introduction/Objective. Implant placement in the posterior maxilla may be often hard to achieve because of insufficient bone volume and the presence of a highly pneumatized maxillary sinus. In these situations, sinus floor augmentation frequently has been proposed as the treatment possibility, conventionally performed utilizing xenograft materials. This research aims to study whether fragmented fat tissue from the Bichat?s fat pad mixed with bovine-derived bone yields better results than the use of bovine-derived bone alone in maxillary sinus augmentation. The secondary aim was to evaluate the influence of low-level light therapy on bone regeneration in patients treated with fragmented fat tissue mixed with bovine-derived bone. Methods. Six patients were included in the study; 12 maxillary sinus augmentation procedures were performed, and patients were randomly assigned into three groups. Six months after surgery a conebeam computed tomography bone density analysis was performed, and resonance frequency analysis (RFA) was performed on 12 placed implants. Results. Bone density results yielded notable differences in Hounsfield units, with experimental groups (499.94 ? 88.43) resembling natural bone more when compared with the control group (674.57 ? 217.12). RFA data shows that the results exhibit a degree of comparability or moderately better stability in the experimental groups (56.88 ? 6.03) compared to the control group (53 ? 20.12). Conclusions. The given Hounsfield units and RFA analysis serve as clear indicators of the substantial potential of fragmented fat tissue and xenograft mixture in maxillary sinus augmentation, by its complete integration and provision of significant stability to the inserted implants. Xenograft mixed with Bichat?s fat pad tissue may represent an important novel entity in the field of bone regeneration.