Impact of phototherapy on serum calcium levels in full-term neonates with hyperbilirubinemia

Objective: The purpose of this study is to investigate the frequency of hypocalcemia in term newborns with neonatal hyperbilirubinemia following phototherapy. Material and Methods: The descriptive case series research was conducted for six months, from August 2020 to February 2021, at the Department of Pediatric Medicine at the Divisional Headquarters Teaching Hospital, Mirpur Azad Kashmir. All patients were enrolled, informed consent was obtained, and they received 48 hours of double surface phototherapy. Routine investigations also included the measurement of serum calcium. Results: The study found a mean age of 14 days, with 63.68% male and 36.32% female cases. Before and after therapy, blood calcium levels averaged 2.41 ± 1.477 mmol/L & 2.5 ± 0.465 mmol/L respectively. Hypocalcemia was seen in 15.79% of patients. The study discovered that the prevalence of hypocalcemia was statistically equal in situations where the baseline blood bilirubin levels before treatment were 85.5-119.7 µmol/L (14.2%) and 121.4-171 µmol/L (16.8%). Conclusion: In conclusion, after 48 hours of phototherapy, 15.79% of the newborns experienced hypocalcemia, indicating that calcium supplementation may be used as a preventative measure to avoid this disease. Keywords: Neonatal jaundice, Calcium supplementation, Phototherapy, Complications.

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Publication Details

Journal
Pakistan Journal of Pathology
Published
2024-12-27
DOI
https://doi.org/10.55629/pakjpathol.v35i4.851
Primary Topic
Neonatal Health and Biochemistry
Type
article
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article

Impact of phototherapy on serum calcium levels in full-term neonates with hyperbilirubinemia

Sehrish Shabbir, Hira Zafar, Asad Ali, Ammara Manzoor et al.
Pakistan Journal of Pathology
Neonatal Health and Biochemistry
article

Impact of phototherapy on serum calcium levels in full-term neonates with hyperbilirubinemia

Sehrish Shabbir, Hira Zafar, Asad Ali, Ammara Manzoor, Hina Farooq, Z. Rasheed
article en

Abstract

Objective: The purpose of this study is to investigate the frequency of hypocalcemia in term newborns with neonatal hyperbilirubinemia following phototherapy. Material and Methods: The descriptive case series research was conducted for six months, from August 2020 to February 2021, at the Department of Pediatric Medicine at the Divisional Headquarters Teaching Hospital, Mirpur Azad Kashmir. All patients were enrolled, informed consent was obtained, and they received 48 hours of double surface phototherapy. Routine investigations also included the measurement of serum calcium. Results: The study found a mean age of 14 days, with 63.68% male and 36.32% female cases. Before and after therapy, blood calcium levels averaged 2.41 ± 1.477 mmol/L & 2.5 ± 0.465 mmol/L respectively. Hypocalcemia was seen in 15.79% of patients. The study discovered that the prevalence of hypocalcemia was statistically equal in situations where the baseline blood bilirubin levels before treatment were 85.5-119.7 µmol/L (14.2%) and 121.4-171 µmol/L (16.8%). Conclusion: In conclusion, after 48 hours of phototherapy, 15.79% of the newborns experienced hypocalcemia, indicating that calcium supplementation may be used as a preventative measure to avoid this disease. Keywords: Neonatal jaundice, Calcium supplementation, Phototherapy, Complications.

Pakistan Journal of PathologyVol. 35(4)
Divisional Headquarters Teaching Hospital Mirpur (PK), Shaheed Mohtarma Benazir Bhutto Medical University (PK)
Good health and well-being
Openalex Percentile: Top 61%
Neonatal Health and Biochemistry
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Impact of phototherapy on serum calcium levels in full-term neonates with hyperbilirubinemia — Sehrish Shabbir, Hira Zafar, et al. · Pakistan Journal of Pathology (2024) | TGRS Research Map | TGRS