Oral Microbiome And Systemic Health: Exploring The Link Between Periodontal Disease And Chronic Conditions

The literature review clearly established that human oral microbiota control oral and systemic health. Current studies show that periodontal disease has close links with chronic diseases such as cardiovascular diseases, diabetes, and rheumatoid arthritis. In the context of this review, the complex interplay between oral microbiota changes, oral inflammation and systemic inflammation will be discussed, with reference to bacterial translocation, immunomodulation, and systemic inflammatory response. Knowledge of these pathways suggests directions regarding intercessions of the human diseases and favors the vital role of dental hygienic practices in reducing body diseases.