Protective mechanism of safflower yellow injection on myocardial ischemia-reperfusion injury in rats by activating NLRP3 inflammasome
SYI can promote myocardial tissue autophagy by regulating NLRP3, thereby attenuating the myocardial inflammatory response and protecting damaged myocardium in I/R rats.
Authors
- Shujuan Xu (ORCID: https://orcid.org/0009-0009-6554-9751)
- Lingmei Li (ORCID: https://orcid.org/0000-0001-7048-7211)
- Gaojie Xin
- Qiong Zhang (ORCID: https://orcid.org/0000-0001-8360-5539)
- Jianhua Fu (ORCID: https://orcid.org/0000-0002-8544-1862)
- Han Xiao (ORCID: https://orcid.org/0000-0003-4124-9411)
- Lei Li (ORCID: https://orcid.org/0000-0001-9333-5667)
- Hao Guo (ORCID: https://orcid.org/0000-0002-3557-8289)
- Lin Li (ORCID: https://orcid.org/0000-0001-5168-7509)
- Zixin Liu
- Ce Cao (ORCID: https://orcid.org/0000-0002-9901-663X)
- YeHao Zhang
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
- Xiyuan Hospital (CN)
- China Academy of Chinese Medical Sciences (CN)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1186/s12906-025-04747-8
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China
- National Science Fund for Distinguished Young Scholars