Nanopore adaptive sampling accurately detects nucleotide variants and improves the characterization of large‐scale rearrangement for the diagnosis of cancer predisposition
Adaptive sampling is suitable for the analysis of germline alterations. Improves the characterization of Large Scale Rearrangement and detects SNV at a minimum coverage of 10x. Allows flexibility of sequencing.
Authors
- Corentin Richard (ORCID: https://orcid.org/0000-0001-9732-0219)
- Romain Boidot (ORCID: https://orcid.org/0000-0001-9956-1737)
- Sandy Chevrier (ORCID: https://orcid.org/0000-0003-0805-791X)
- Denis Bertrand
- M.-L. Mille
Institutions
- Centre Georges François Leclerc (FR)
- Quantum Genomics (France) (FR)
Publication Details
- Journal
- Clinical and Translational Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1002/ctm2.70138
- Citations
- 7
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 6.55
Funders
- Oxford Nanopore Technologies