Pre-biologic FeNO might predict anti-IL-5/IL-5Rα response to treatment in severe asthmatics
Pre-biologic FeNO might predict a greater response to treatment with anti-IL-5/5R especially in terms of lung function and OC sparing in subjects with severe eosinophilic/allergic asthma. This could likely be a biomarker that can better guide in choosing an anti-IL5/5R in severe overlapping asthma (eosinophilic/allergic) to maximize treatment effects.
Authors
- Bruno Sposato (ORCID: https://orcid.org/0000-0003-4439-7209)
- Nicola Scichilone (ORCID: https://orcid.org/0000-0001-6400-6573)
- Paolo Cameli (ORCID: https://orcid.org/0000-0001-8639-2882)
- Girolamo Pelaia (ORCID: https://orcid.org/0000-0001-9288-8913)
- Corrado Pelaia (ORCID: https://orcid.org/0000-0002-4236-7367)
- Mauro Maniscalco (ORCID: https://orcid.org/0000-0001-6751-9921)
- Simonetta Masieri (ORCID: https://orcid.org/0000-0003-0423-9505)
- Elena Bargagli (ORCID: https://orcid.org/0000-0002-8351-3703)
- Paola Rogliani (ORCID: https://orcid.org/0000-0001-7801-5040)
- Marco Scalese (ORCID: https://orcid.org/0000-0002-7470-2422)
- Giovanna Elisiana Carpagnano (ORCID: https://orcid.org/0000-0001-7931-4704)
- Antonio Perrella
- Leonardo Gianluca Lacerenza (ORCID: https://orcid.org/0000-0002-9315-1654)
- Carlo Cavaliere (ORCID: https://orcid.org/0000-0002-0378-8935)
- Alberto Rícci (ORCID: https://orcid.org/0000-0002-1718-1587)
- Stefano Baglioni (ORCID: https://orcid.org/0000-0002-5250-2868)
- Gianna Camiciottoli (ORCID: https://orcid.org/0000-0002-9742-8550)
- Pierachille Santus
- Pierluigi Paggiaro
- Angelo Guido Corsico
- Dejan Radovanovic
Institutions
- University of Siena (IT)
- University of Pisa (IT)
- University of Rome Tor Vergata (IT)
- University of Milan (IT)
- Magna Graecia University (IT)
- Luigi Sacco Hospital (IT)
- European Society for Sexual Medicine (IT)
- Istituti Clinici Scientifici Maugeri (IT)
- Department of Health (ES)
- Ospedale Santa Maria (IT)
- Federico II University Hospital (IT)
- Azienda Ospedaliera Sant'Andrea (IT)
- Ospedale Misericordia - Grosseto (IT)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Usl Toscana Centro (IT)
- National Medical Research Center of Dentistry and Maxillofacial Surgery (RU)
- Czech Academy of Sciences, Institute of Physiology (CZ)
- University of Florence (IT)
- University of Bari Aldo Moro (IT)
- Misericordia University (US)
- University of Naples Federico II (IT)
- Sapienza University of Rome (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Journal of Asthma
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1080/02770903.2025.2451691
- Citations
- 2
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.33