Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury

Our findings provide valuable insights into the interconnection between CAMs and compensatory mechanisms in controlling leukocyte migration in AKI and CKD. The combination of multiple CAM blockers, given simultaneously, may provide protective effects for preventing excessive leukocyte infiltration and control renal injury.

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Publication Details

Journal
Pharmaceutics
Published
2025-01-09
DOI
https://doi.org/10.3390/pharmaceutics17010082
Citations
2
Primary Topic
Cell Adhesion Molecules Research
Type
article
Field-Weighted Citation Impact
3.24

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article

Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury

Ayelet David, Nenad Milošević, Yvonne Ventura, Valeria Feinshtein et al.
2 citations
Pharmaceutics
Cell Adhesion Molecules Research
3.24
article

Targeted Polymer–Peptide Conjugates for E-Selectin Blockade in Renal Injury

Ayelet David, Nenad Milošević, Yvonne Ventura, Valeria Feinshtein, Marie Rütter
article en
2 citations

Abstract

Our findings provide valuable insights into the interconnection between CAMs and compensatory mechanisms in controlling leukocyte migration in AKI and CKD. The combination of multiple CAM blockers, given simultaneously, may provide protective effects for preventing excessive leukocyte infiltration and control renal injury.

PharmaceuticsVol. 17(1)
Ben-Gurion University of the Negev (IL)
Fondation Leducq, Israel Science Foundation, Ben-Gurion University of the Negev
Good health and well-being
Openalex Percentile: Top 12%
Cell Adhesion Molecules Research
3.24
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