A Series of 40 Congenital Lung Malformation Cases and the Informative Value of CPAM Lesion Ratios

If patients present no symptoms, mild symptoms, or smaller CPAM lesions, "wait and watch" and a CT scan of the thorax up to approximately six months of age remain a reasonable approach. The true risk of malignancy remains ambiguous, especially since there was no evidence of malignancy in our biopsies. On the other hand, prophylactic surgery before symptoms arose led to earlier discharge and overall low intraoperative complications compared to symptomatic counterparts. Ultimately, the adopted therapy pathway remains a parental choice. For CPAMs, an increased lesion-to-lung ratio correlated with extended hospital stay and symptomatic presentation. However, there was no cut-off value for conservative or surgical treatment.

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Journal
Pediatric Reports
Published
2025-01-09
DOI
https://doi.org/10.3390/pediatric17010005
Citations
1
Primary Topic
Congenital Diaphragmatic Hernia Studies
Type
article
Field-Weighted Citation Impact
2.01
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article

A Series of 40 Congenital Lung Malformation Cases and the Informative Value of CPAM Lesion Ratios

Carl-Martin Junge, Christian Tomuschat, Konrad Reinshagen, Kersten Peldschus et al.
1 citations
Pediatric Reports
Congenital Diaphragmatic Hernia Studies
2.01
article

A Series of 40 Congenital Lung Malformation Cases and the Informative Value of CPAM Lesion Ratios

Carl-Martin Junge, Christian Tomuschat, Konrad Reinshagen, Kersten Peldschus, Melanie Le, Phillip Harms
article en
1 citations

Abstract

If patients present no symptoms, mild symptoms, or smaller CPAM lesions, "wait and watch" and a CT scan of the thorax up to approximately six months of age remain a reasonable approach. The true risk of malignancy remains ambiguous, especially since there was no evidence of malignancy in our biopsies. On the other hand, prophylactic surgery before symptoms arose led to earlier discharge and overall low intraoperative complications compared to symptomatic counterparts. Ultimately, the adopted therapy pathway remains a parental choice. For CPAMs, an increased lesion-to-lung ratio correlated with extended hospital stay and symptomatic presentation. However, there was no cut-off value for conservative or surgical treatment.

Pediatric ReportsVol. 17(1)
Universität Hamburg (DE), University Medical Center Hamburg-Eppendorf (DE), Kinderkrebs-Zentrum Hamburg (DE)
Good health and well-being
Openalex Percentile: Top 20%
Congenital Diaphragmatic Hernia Studies
2.01
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A Series of 40 Congenital Lung Malformation Cases and the Informative Value of CPAM Lesion Ratios — Carl-Martin Junge, Christian Tomuschat, et al. · Pediatric Reports (2025) | TGRS Research Map | TGRS