A Series of 40 Congenital Lung Malformation Cases and the Informative Value of CPAM Lesion Ratios
If patients present no symptoms, mild symptoms, or smaller CPAM lesions, "wait and watch" and a CT scan of the thorax up to approximately six months of age remain a reasonable approach. The true risk of malignancy remains ambiguous, especially since there was no evidence of malignancy in our biopsies. On the other hand, prophylactic surgery before symptoms arose led to earlier discharge and overall low intraoperative complications compared to symptomatic counterparts. Ultimately, the adopted therapy pathway remains a parental choice. For CPAMs, an increased lesion-to-lung ratio correlated with extended hospital stay and symptomatic presentation. However, there was no cut-off value for conservative or surgical treatment.
Authors
- Carl-Martin Junge
- Christian Tomuschat (ORCID: https://orcid.org/0000-0001-9028-4163)
- Konrad Reinshagen (ORCID: https://orcid.org/0000-0001-7142-8758)
- Kersten Peldschus
- Melanie Le (ORCID: https://orcid.org/0000-0001-7239-3411)
- Phillip Harms
Institutions
- Universität Hamburg (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- Kinderkrebs-Zentrum Hamburg (DE)
Publication Details
- Journal
- Pediatric Reports
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3390/pediatric17010005
- Citations
- 1
- Primary Topic
- Congenital Diaphragmatic Hernia Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01