DET induces apoptosis and suppresses tumor invasion in glioma cells via PI3K/AKT pathway
DET inhibits GBM cell invasion, proliferation, and apoptosis via modulating the PI3K/AKT signaling pathway, highlighting its potential as a novel therapeutic strategy for GBM treatment.
Authors
- Xiaochun Jiang (ORCID: https://orcid.org/0000-0003-0246-1292)
- Chenghui Zhao (ORCID: https://orcid.org/0000-0003-2059-630X)
- Shizhang Ling (ORCID: https://orcid.org/0000-0002-6856-3577)
- Min Qi (ORCID: https://orcid.org/0009-0000-5474-1822)
- Yue Su (ORCID: https://orcid.org/0000-0002-6987-3737)
- Huiling Dong
- Panpan Zhao (ORCID: https://orcid.org/0009-0001-2608-7218)
- Mengran Wang (ORCID: https://orcid.org/0000-0002-0241-5643)
- Rui Zhao (ORCID: https://orcid.org/0000-0003-4884-474X)
- Zeyu Wu (ORCID: https://orcid.org/0000-0002-3895-9976)
Institutions
- Wannan Medical College (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-01-09
- DOI
- https://doi.org/10.3389/fonc.2024.1528454
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Anhui Provincial Department of Education