Acute Decompensated Heart Failure: Structural and Functional Changes in Mitochondria

A decrease in the total area of interfibrillar mitochondria of the right atrial appendage cardiomyocytes of less than 32% as measured by electron microscopy is characteristic of patients with a previous episode of ADHF with reduced and moderately reduced left ventricular ejection fraction. The study results confirm the development and persistence of ultrastructural changes in cardiomyocytes after ADHF.

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Publication Details

Journal
Kardiologiia
Published
2024-12-24
DOI
https://doi.org/10.18087/cardio.2024.12.n2737
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
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article

Acute Decompensated Heart Failure: Structural and Functional Changes in Mitochondria

K. N. Vitt, Ekaterina E. Syromyatnikova, Olga V. Tukish, В. А. Корепанов et al.
Kardiologiia
Cardiovascular Function and Risk Factors
article

Acute Decompensated Heart Failure: Structural and Functional Changes in Mitochondria

K. N. Vitt, Ekaterina E. Syromyatnikova, Olga V. Tukish, В. А. Корепанов, С. Л. Андреев, Гарганеева Алла Анатольевна, Кужелева Елена Андреевна, S. A. Аfanasiev, Mikhail Yu. Kondratiev, Yu. A. Arsenieva
article en

Abstract

A decrease in the total area of interfibrillar mitochondria of the right atrial appendage cardiomyocytes of less than 32% as measured by electron microscopy is characteristic of patients with a previous episode of ADHF with reduced and moderately reduced left ventricular ejection fraction. The study results confirm the development and persistence of ultrastructural changes in cardiomyocytes after ADHF.

KardiologiiaVol. 64(12)
Russian Academy of Sciences (RU), Tomsk National Research Medical Center (RU)
Good health and well-being
Openalex Percentile: Top 55%
Cardiovascular Function and Risk Factors
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