Odontogenic Sinusitis of Endodontic Origin: Successful Management Through Endodontic Treatment

Odontogenic sinusitis is a maxillary sinus infection arising from dental pathology, primarily involving posterior maxillary teeth due to their anatomical proximity to the sinus floor. Endodontic infections are a significant etiological factor, yet the condition is frequently underdiagnosed due to its overlapping presentation with sinonasal sinusitis. The present cases illustrate the diagnosis, management, and outcomes of maxillary sinusitis of endodontic origin through endodontic interventions. Two patients with histories of recurrent maxillary sinusitis underwent dental evaluations after conventional medical therapies failed. Cone-beam computed tomography confirmed the dental etiology in all cases, identifying inadequately treated second mesiobuccal (MB2) canals or significant periapical pathology. Endodontic retreatments were employed to address the underlying dental causes, followed by resolution of sinus symptoms within days. Follow-up imaging demonstrated ongoing bone healing and resolution of sinus involvement. These cases underscore the importance of addressing the dental etiology in maxillary sinusitis of endodontic origin to achieve complete symptom resolution and minimize recurrence. Cone-beam computed tomography proved instrumental in diagnosing and planning treatment, enabling precise management of periapical and sinus conditions. The cases highlight the necessity of a multidisciplinary approach, involving dental and medical professionals, to optimize outcomes.