miRNA Expression Profile in Primary Limbal Epithelial Cells of Aniridia Patients
This study revealed miRNA expression profile in pLECs of patients with aniridia using miRNA microarray and identified miRNAs that had not been previously reported for aniridia LECs. Our study also provides functional and pathway information that can be used to predict possible mechanism of miRNA function in LECs, thereby bridging the gap in the pathogenesis of AAK studies.
Authors
- Tanja Stachon (ORCID: https://orcid.org/0000-0001-7009-7125)
- Nicole Ludwig (ORCID: https://orcid.org/0000-0003-4703-7567)
- Maryam Amini (ORCID: https://orcid.org/0009-0000-3118-9959)
- Eckart U. Meese (ORCID: https://orcid.org/0000-0001-7569-819X)
- Mahsa Nastaranpour
- Shweta Suiwal (ORCID: https://orcid.org/0000-0002-1230-1279)
- Nóra Szentmáry (ORCID: https://orcid.org/0000-0001-8019-1481)
- Fabian Norbert Fries (ORCID: https://orcid.org/0000-0002-8526-4712)
- Berthold Seitz (ORCID: https://orcid.org/0000-0001-9701-8204)
Institutions
- Saarland University (DE)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1167/iovs.66.1.20
- Citations
- 8
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 10.88
Funders
- Deutsche Forschungsgemeinschaft