Exploring the potential of gemcitabine-metal–organic frameworks in combating pancreatic cancer under ketogenic conditions
The use of metal-organic framework to encapsulate gemcitabine yielded notable pro-apoptotic effects in MIA-PaCa-2 cells with which ketogenic conditions had a synergistic effect that can hold promise for improving therapeutic options.
Authors
- Behzad Baradaran (ORCID: https://orcid.org/0000-0002-8642-6795)
- Samira Nekoufar
- Masoumeh Tavakoli‐Yaraki (ORCID: https://orcid.org/0000-0003-4449-9248)
- Farzad Izak Shirian
- Sahar Safaei (ORCID: https://orcid.org/0000-0001-7181-9396)
- Marjan Ghorbani (ORCID: https://orcid.org/0000-0002-2500-6930)
- Gholamreza Alinezhadi Khosroushahi
Institutions
- Iran University of Medical Sciences (IR)
- Tabriz University of Medical Sciences (IR)
- University of Tabriz (IR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1186/s12885-024-13397-x
- Citations
- 4
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Iran University of Medical Sciences