PRMT1-Mediated Arginine Methylation Promotes Corneal Epithelial Wound Healing via Epigenetic Regulation of ANXA3
PRMT1 is a critical epigenetic regulator in CEWH, promoting wound healing by upregulating ANXA3 via histone arginine methylation. These findings highlight the potential of targeting PRMT1 to enhance corneal epithelial repair.
Authors
- Dongsheng Yan (ORCID: https://orcid.org/0000-0003-0551-2219)
- Guangying Luo (ORCID: https://orcid.org/0000-0003-1400-2130)
- Peter S. Reinach (ORCID: https://orcid.org/0000-0002-3494-4523)
- Qiongjie Cao
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Wenji Xu
Institutions
- Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1167/iovs.66.1.22
- Citations
- 4
- Primary Topic
- Cancer-related gene regulation
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- McGill University
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province