A strategy to increase identification of patients with Familial Hypercholesterolemia: Application of the Simon Broome lipid criteria in a large-scale retrospective analysis

A laboratory-developed algorithm using Simon Broome lipid criteria can help identify patients who may benefit from additional FH evaluation. While critical, testing hyperlipidemic children for FH is grossly underutilized, as is genetic testing for FH. Diagnostic laboratories are uniquely positioned to bring FH to the attention of clinicians, with the goal of earlier diagnosis, cascade testing, and appropriate treatment.