Deconditioning in quiescent Crohn’s disease patients with heightened fatigue perception
CD self-reported increased fatigue perception and exhibited a slower rate of post-exercise PCr resynthesis compared to HV. This occurred independently of changes in body composition, muscle strength, and fatigability. IBD fatigue may be linked to peripheral muscle deconditioning and lower gmCBF during submaximal exercise.
Authors
- Stephen Bawden (ORCID: https://orcid.org/0000-0002-5157-3269)
- Sébastien Serres (ORCID: https://orcid.org/0000-0002-1573-1581)
- Rosemary Nicholas (ORCID: https://orcid.org/0000-0003-4745-1821)
- Susan Francis (ORCID: https://orcid.org/0000-0003-0903-7507)
- Shellie Jean Radford (ORCID: https://orcid.org/0000-0002-2226-0810)
- Jordan McGing (ORCID: https://orcid.org/0000-0002-1238-0472)
- Joanne Mallinson (ORCID: https://orcid.org/0000-0003-1275-2448)
- Gordon W. Moran (ORCID: https://orcid.org/0000-0002-8906-6908)
- Christopher Bradley
- Paul L. Greenhaff (ORCID: https://orcid.org/0000-0003-4403-0490)
- A Gupta (ORCID: https://orcid.org/0000-0002-2345-545X)
- Aline Nixon
Institutions
- Mansfield University (US)
- University of Nottingham (GB)
- Singleton Hospital (GB)
- Arthritis UK (GB)
- Nottingham Biomedical Research Centre (GB)
Publication Details
- Journal
- Journal of Crohn s and Colitis
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/ecco-jcc/jjae194
- Citations
- 6
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Crohn's and Colitis UK
- Medical Research Council