Pseudoepitheliomatous hyperplasia misdiagnosed as cutaneous squamous cell carcinoma: a case report

Pseudoepitheliomatous hyperplasia (PEH) is a rare histopathological reaction. Cases of PEH have been infrequently reported, and it's even rare to appear as a postsurgical complication. This case report describes the development of multiple masses and purulent discharge around an abdominal scar following surgery for hepatocellular carcinoma, which morphologically resembles squamous cell carcinoma (SCC), though pathology revealed no signs of malignancy. The underlying mechanism of PEH has not been fully characterized. This case report may alert clinicians and pathologists to rare diseases and update the list of postoperative complications.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2024-12-21
DOI
https://doi.org/10.1093/jscr/rjae838
Primary Topic
Tumors and Oncological Cases
Type
article
Field-Weighted Citation Impact
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article

Pseudoepitheliomatous hyperplasia misdiagnosed as cutaneous squamous cell carcinoma: a case report

Hongyu Ruan, Songting Wang, Xinyu Jiang, G. LI et al.
Journal of Surgical Case Reports
Tumors and Oncological Cases
article

Pseudoepitheliomatous hyperplasia misdiagnosed as cutaneous squamous cell carcinoma: a case report

Hongyu Ruan, Songting Wang, Xinyu Jiang, G. LI, Suling Xu, Xiaoxia Zhu, Feng Yang, Keyu Zhao
article en

Abstract

Pseudoepitheliomatous hyperplasia (PEH) is a rare histopathological reaction. Cases of PEH have been infrequently reported, and it's even rare to appear as a postsurgical complication. This case report describes the development of multiple masses and purulent discharge around an abdominal scar following surgery for hepatocellular carcinoma, which morphologically resembles squamous cell carcinoma (SCC), though pathology revealed no signs of malignancy. The underlying mechanism of PEH has not been fully characterized. This case report may alert clinicians and pathologists to rare diseases and update the list of postoperative complications.

Journal of Surgical Case ReportsVol. 2025(1)
Ningbo University (CN)
Good health and well-being
Openalex Percentile: Top 60%
Tumors and Oncological Cases
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Pseudoepitheliomatous hyperplasia misdiagnosed as cutaneous squamous cell carcinoma: a case report — Hongyu Ruan, Songting Wang, et al. · Journal of Surgical Case Reports (2024) | TGRS Research Map | TGRS