Acquired reactive perforating collagenosis in skin of color

Acquired reactive perforating collagenosis is an uncommon disorder that present as keratotic plugs on the skin owing to transepidermal perforation of dermal connective tissue. Etiology is unclear, although the condition has been associated with renal disease, diabetes, and HIV. It can frequently be misdiagnosed and lead to significant impact on quality of life, particularly in patients with skin of color. Herein, we present an skin of color patient with this condition who experienced severe pruritus over years before receiving a definitive diagnosis. Clobetasol improved her condition and quality of life over several months.

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Publication Details

Journal
Dermatology Online Journal
Published
2025-01-09
DOI
https://doi.org/10.5070/d330664686
Primary Topic
Dermatological and Skeletal Disorders
Type
article
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article

Acquired reactive perforating collagenosis in skin of color

Maryam Abdo, Spencer P. McClure, William Liakos, Edward W. Seger et al.
Dermatology Online Journal
Dermatological and Skeletal Disorders
article

Acquired reactive perforating collagenosis in skin of color

Maryam Abdo, Spencer P. McClure, William Liakos, Edward W. Seger, Ryan Gillihan, Anne-Marie Murray
article en

Abstract

Acquired reactive perforating collagenosis is an uncommon disorder that present as keratotic plugs on the skin owing to transepidermal perforation of dermal connective tissue. Etiology is unclear, although the condition has been associated with renal disease, diabetes, and HIV. It can frequently be misdiagnosed and lead to significant impact on quality of life, particularly in patients with skin of color. Herein, we present an skin of color patient with this condition who experienced severe pruritus over years before receiving a definitive diagnosis. Clobetasol improved her condition and quality of life over several months.

Dermatology Online JournalVol. 30(6)
University of Kansas Medical Center (US)
Good health and well-being
Openalex Percentile: Top 100%
Dermatological and Skeletal Disorders
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