Impact of Granulocyte Colony-Stimulating Factor (G-CSF) on Clinical Outcomes in Allogeneic Hematopoietic Cell Transplantation: Does Speeding Up Neutrophil Engraftment Make a Difference?

Although G-CSF post-HCT expedited neutrophil engraftment and reduced BSI risk, it did not result in a survival advantage. The association with ES necessitates careful consideration.

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Publication Details

Journal
Transplantation Direct
Published
2025-01-09
DOI
https://doi.org/10.1097/txd.0000000000001753
Primary Topic
Neutropenia and Cancer Infections
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of Granulocyte Colony-Stimulating Factor (G-CSF) on Clinical Outcomes in Allogeneic Hematopoietic Cell Transplantation: Does Speeding Up Neutrophil Engraftment Make a Difference?

Carol Chen, Rajat Kumar, Armin Gerbitz, Mats Remberger et al.
Transplantation Direct
Neutropenia and Cancer Infections
article

Impact of Granulocyte Colony-Stimulating Factor (G-CSF) on Clinical Outcomes in Allogeneic Hematopoietic Cell Transplantation: Does Speeding Up Neutrophil Engraftment Make a Difference?

Carol Chen, Rajat Kumar, Armin Gerbitz, Mats Remberger, Igor Novitzky‐Basso, Dennis Kim, Eshrak Al‐Shaibani, Arjun Law, Ahmed Alnughmush, Ivan Pašić, Auro Viswabandya, Fotios V. Michelis, Jonas Mattsson, Caden Chiarello, Wilson Lam, Ayman Sayyed
article en

Abstract

Although G-CSF post-HCT expedited neutrophil engraftment and reduced BSI risk, it did not result in a survival advantage. The association with ES necessitates careful consideration.

Transplantation DirectVol. 11(2)
Uppsala University Hospital (SE), University of Toronto (CA), King Faisal Specialist Hospital & Research Centre (SA), Princess Margaret Cancer Centre (CA), NOSM University (CA)
Good health and well-being
Openalex Percentile: Top 99%
Neutropenia and Cancer Infections
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