Methylome profiling of cell-free DNA during the early life course in (un)complicated pregnancies using MeD-seq: Protocol for a cohort study embedded in the prospective Rotterdam periconception cohort
This study will provide insights in placental DNA methylation dynamics in health and disease, and could lead to clinical relevant biomarkers.
Authors
- Ruben Boers (ORCID: https://orcid.org/0000-0002-3377-2897)
- Régine P.M. Steegers‐Theunissen (ORCID: https://orcid.org/0000-0002-4353-5756)
- Marjolein M. van Vliet (ORCID: https://orcid.org/0000-0001-5476-037X)
- Sam Schoenmakers (ORCID: https://orcid.org/0000-0002-0316-6159)
- Lotte E. van der Meeren (ORCID: https://orcid.org/0000-0002-4537-5645)
- Joost H. Gribnau (ORCID: https://orcid.org/0000-0001-5645-4691)
Institutions
- Leiden University Medical Center (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-01-09
- DOI
- https://doi.org/10.1371/journal.pone.0310019
- Citations
- 6
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 20.96