Time-Resolved Effects of Short-term Overfeeding on Energy Balance in Mice
Intragastric overfeeding reveals insights into the homeostatic recovery from experimental weight gain. Protection against short-term, overfeeding-induced weight gain primarily involves a profound reduction in food intake and possibly an adaptive increase in energy expenditure. UCP1-mediated thermogenesis is not essential for homeostatic protection against short-term, overfeeding-induced weight gain.
Authors
- Pablo Ranea‐Robles (ORCID: https://orcid.org/0000-0001-6478-3815)
- Maximilian Kleinert (ORCID: https://orcid.org/0000-0002-8069-9055)
- Camilla Lund (ORCID: https://orcid.org/0000-0001-5162-7311)
- Jens Lund (ORCID: https://orcid.org/0000-0003-2338-6033)
- Charlotte Svendsen (ORCID: https://orcid.org/0000-0002-8329-319X)
- Cláudia Gil (ORCID: https://orcid.org/0000-0002-5033-4143)
- Christoffer Clemmensen (ORCID: https://orcid.org/0000-0003-2456-9667)
Institutions
- University of Copenhagen (DK)
- Universidad de Granada (ES)
- Novo Nordisk Foundation (DK)
- Instituto de Investigación Biosanitaria de Granada (ES)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Center for Diabetes Research (DE)
- German Institute of Human Nutrition (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Diabetes
- Published
- 2025-01-09
- DOI
- https://doi.org/10.2337/db24-0289
- Citations
- 2
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.33
Funders
- Deutsche Forschungsgemeinschaft
- Lundbeckfonden
- Novo Nordisk
- Technische Universität München
- Copenhagen Graduate School for Nanoscience and Nanotechnology
- Faculty of Health and Medical Sciences, University of Western Australia
- Novo Nordisk Fonden
- Novo Nordisk Foundation Center for Basic Metabolic Research
- H. Lundbeck A/S
- Centro de Investigação em Biomedicina
- Det Sundhedsvidenskabelige Fakultet, Københavns Universitet
- European Regional Development Fund